CYANOCOBALAMIN (VITHAMINI B12)
Sebopeho le Matlotlo
Sehlahisoa sena ke phofo e khubelu ea kristale kapa kristale, ha e na monko, ha e na tatso 'me e na le thepa e matla e bakang mongobo. E qhibiliha hanyane ka metsing kapa ethanol, ha e qhibilihe ka har'a chloroform kapa ether. E hanela mocheso, empa e ka se sebetse ha e pepesehetse lintho tse oxidisang kapa tse fokotsang, matsoai a tšepe e boima le li-acid tse matla le li-alkali tse matla.
Sebopeho sa Lik'hemik'hale
Vithamine B12 ke motsoako oa equioctaphedral o nang le li-ion tsa cobalt. Sebopeho sa eona se bohareng ke lesale le bataletseng la corrin le entsoeng ka li-pyrrole tse 'ne tse hokahaneng. Limolek'hule tsa vithamine B12 li entsoe ka likarolo tse 3: lesale la gourin le chylated ke liathomo tse 'ne tsa N le li-ion tsa cobalt tse bohareng; 5,6-dimethylbenzimidazole e hokahaneng le liathomo tsa N-7 le li-ion tsa cobalt e le limolek'hule tsa vithamine B 12 tsa ligands tse maemong a tlase. Ho phaella moo, DMBI e boetse e hokahane le aminopropanol ka lihlopha tsa phosphate, 'me aminopropanol e hokahane ka kopanelo le ketane ea lehlakore la propionic acid ho pyrrole D; sehlopha sa adenosyl kapa sehlopha sa methyl. E hokahane le li-ion tsa cobalt ho theha ligand e kaholimo ea limolek'hule tsa vithamine B12.
Mosebetsi oa 'mele
Khaello ea vithamine B12 e ka lebisa ho peripheral neuritis. Lipontšo tsa pele tsa khaello ea vithamine B12 ho bana ke maikutlo a sa tloaelehang, ho hlahisa maikutlo butle, karabelo e liehang, 'me qetellong li lebisa ho haelloa ke mali. Ho khothalletsa nts'etsopele le khōlo ea lisele tse khubelu tsa mali. Methylpropandiyl coenzyme A e fetoloa hore e be succinoyl coenzyme A 'me e nka karolo potolohong ea tricarboxylic acid, moo succinyl coenzyme A e amanang le ho etsoa ha heme. Vithamine B12 e boetse e nka karolo ho etseng deoxynucleic acid (DNA), metabolism ea mafura, lik'habohaedreite le protheine, 'me e eketsa ho etsoa ha nucleic acid le liprotheine.
